| 1 |
35505646 | Non-phosphorylated Tyr-1248 form of human epidermal growth factor receptor 2 (HER2) predicts resistance to trastuzumab therapy and poor disease-free survival of HER2-positive breast cancer patients. | 2022 Apr 30 |
3 |
| 2 |
32964398 | The G Protein-Coupled Receptor PAC1 Regulates Transactivation of the Receptor Tyrosine Kinase HER3. | 2021 Aug |
2 |
| 3 |
33514658 | Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells. | 2021 May |
1 |
| 4 |
33620127 | Molecular dynamics simulation studies on the specific regulation of PTPN18 to the HER2 phospho-peptides. | 2021 Jul |
1 |
| 5 |
34066157 | Tumor Extrinsic Factors Mediate Primary T-DM1 Resistance in HER2-Positive Breast Cancer Cells. | 2021 May 12 |
4 |
| 6 |
34232285 | The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands. | 2021 Jul 30 |
1 |
| 7 |
31471681 | Mechanisms of resistance to estrogen receptor modulators in ER+/HER2- advanced breast cancer. | 2020 Feb |
1 |
| 8 |
31736196 | Sensitization of HT29 colorectal cancer cells to vemurafenib in three-dimensional collagen cultures. | 2020 Feb |
1 |
| 9 |
31755215 | Photobodies: Light-Activatable Single-Domain Antibody Fragments. | 2020 Jan 20 |
1 |
| 10 |
31825569 | Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer. | 2020 Feb 13 |
1 |
| 11 |
31830556 | Proliferative signaling by ERBB proteins and RAF/MEK/ERK effectors in polycystic kidney disease. | 2020 Mar |
2 |
| 12 |
31901678 | Systematic molecular profiling of inhibitor response to the clinical missense mutations of ErbB family kinases in human gastric cancer. | 2020 May |
1 |
| 13 |
31980423 | An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway. | 2020 Jan 24 |
1 |
| 14 |
31991749 | Structure-Activity Relationship of HER2 Receptor Targeting Peptide and Its Derivatives in Targeted Tumor Therapy. | 2020 Jan 25 |
1 |
| 15 |
32006616 | Targeting the EphB4 receptor tyrosine kinase sensitizes HER2-positive breast cancer cells to Lapatinib. | 2020 Apr 10 |
1 |
| 16 |
32017710 | Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors. | 2020 May 1 |
1 |
| 17 |
32024694 | A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2). | 2020 Mar 13 |
1 |
| 18 |
32267234 | Single-molecule functional anatomy of endogenous HER2-HER3 heterodimers. | 2020 Apr 8 |
1 |
| 19 |
32291971 | Mutational landscape and characteristics of ERBB2 in non-small cell lung cancer. | 2020 Jun |
1 |
| 20 |
32584853 | Trastuzumab effects depend on HER2 phosphorylation in HER2-negative breast cancer cell lines. | 2020 |
3 |
| 21 |
30273693 | PAC1 regulates receptor tyrosine kinase transactivation in a reactive oxygen species-dependent manner. | 2019 Oct |
1 |
| 22 |
30317579 | Tyrosine phosphorylation of HDAC3 by Src kinase mediates proliferation of HER2-positive breast cancer cells. | 2019 May |
1 |
| 23 |
31569723 | Proteasome Inhibitors Suppress ErbB Family Expression through HSP90-Mediated Lysosomal Degradation. | 2019 Sep 27 |
1 |
| 24 |
31607147 | Mechanisms of the Multitasking Endothelial Protein NRG-1 as a Compensatory Factor During Chronic Heart Failure. | 2019 Oct |
1 |
| 25 |
31614143 | Neurotensin receptors regulate transactivation of the EGFR and HER2 in a reactive oxygen species-dependent manner. | 2019 Dec 15 |
1 |
| 26 |
31656036 | The role of autophagy in HER2-targeted therapy. | 2019 Oct 7 |
1 |
| 27 |
31686753 | Prognostic Value of HER-2/neu Gene Amplification in Epithelial Ovarian Carcinoma. | 2019 Oct |
2 |
| 28 |
31689531 | Endocytic degradation of ErbB2 mediates the effectiveness of neratinib in the suppression of ErbB2-positive ovarian cancer. | 2019 Dec |
1 |
| 29 |
31720077 | Mechanism, safety and efficacy of three tyrosine kinase inhibitors lapatinib, neratinib and pyrotinib in HER2-positive breast cancer. | 2019 |
2 |
| 30 |
31763355 | Automatic quantification of HER2 gene amplification in invasive breast cancer from chromogenic in situ hybridization whole slide images. | 2019 Oct |
3 |
| 31 |
31831814 | Nectin-4 cis-interacts with ErbB2 and its trastuzumab-resistant splice variants, enhancing their activation and DNA synthesis. | 2019 Dec 12 |
1 |
| 32 |
31839995 | Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. | 2019 |
1 |
| 33 |
31921382 | Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy. | 2019 Dec 31 |
1 |
| 34 |
29434871 | Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways. | 2018 Feb |
2 |
| 35 |
29453318 | Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance. | 2018 May |
1 |
| 36 |
30067338 | Analysis of MEMO1 Binding Specificity for ErbB2 Using Fluorescence Polarization and Molecular Dynamics Simulations. | 2018 Aug 28 |
1 |
| 37 |
30098331 | Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation. | 2018 Oct 1 |
1 |
| 38 |
30174304 | Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway. | 2018 Dec 4 |
1 |
| 39 |
27787847 | Characterizing ErbB-2-Mediated Tyrosine Phosphorylation and Activation of Plexins. | 2017 |
1 |
| 40 |
27842890 | New small 99mTc-labeled peptides for HER2 receptor imaging. | 2017 Feb 15 |
1 |
| 41 |
28102081 | Deep Coverage of Global Protein Expression and Phosphorylation in Breast Tumor Cell Lines Using TMT 10-plex Isobaric Labeling. | 2017 Mar 3 |
2 |
| 42 |
28218905 | Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. | 2017 Jul 6 |
1 |
| 43 |
28263756 | Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts. | 2017 Apr |
2 |
| 44 |
28722233 | Cooperative interaction of hepatocyte growth factor and neuregulin regulates Schwann cell migration and proliferation through Grb2-associated binder-2 in peripheral nerve repair. | 2017 Nov |
1 |
| 45 |
28900130 | Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB2. | 2017 Sep 12 |
2 |
| 46 |
28974323 | Synthesis and photophysical properties of a fluorescent cyanoquinoline probe for profiling ERBB2 kinase inhibitor response. | 2017 Nov 1 |
3 |
| 47 |
26676300 | Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells. | 2016 Feb |
3 |
| 48 |
27531070 | Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain. | 2016 Aug 17 |
1 |
| 49 |
24395385 | p66Shc longevity protein regulates the proliferation of human ovarian cancer cells. | 2015 Aug |
1 |
| 50 |
25326580 | HER2 activation results in β-catenin-dependent changes in pulmonary epithelial permeability. | 2015 Jan 15 |
1 |