Irinotecan

ATP binding cassette subfamily C member 1 ; Homo sapiens







18 Article(s)
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Pub. Year
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1 34365218 Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. 2021 Nov 1
2 30925062 Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach. 2019 May 9 1
3 27845419 ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia. 2018 Jan 3
4 29499902 Effect of UGT, SLCO, ABCB and ABCC polymorphisms on irinotecan toxicity. 2018 Dec 14 1
5 29016119 9-Deazapurines as Broad-Spectrum Inhibitors of the ABC Transport Proteins P-Glycoprotein, Multidrug Resistance-Associated Protein 1, and Breast Cancer Resistance Protein. 2017 Nov 9 1
6 26950035 MRP1 expression in CTCs confers resistance to irinotecan-based chemotherapy in metastatic colorectal cancer. 2016 Aug 15 6
7 26352872 ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients. 2015 Dec 1
8 21529984 Klotho predicts good clinical outcome in patients with limited-disease small cell lung cancer who received surgery. 2011 Nov 1
9 21787264 Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity. 2011 Dec 1
10 20726333 Hepatocyte growth factor (HGF), heat shock proteins (HSPs) and multidrug resistance protein (MRP) expression in co-culture of colon tumor spheroids with normal cells after incubation with interleukin-1beta (IL-1beta) and/or camptothecin (CPT-11). 2010 Apr 1
11 19349540 Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. 2009 Jun 1 2
12 20093746 Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11. 2009 Dec 1
13 18690847 Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy. 2008 Aug 1
14 16508919 Expression of drug pathway proteins is independent of tumour type. 2006 Jun 1
15 15897249 Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors. 2005 May 3
16 16132345 Human multidrug resistance associated protein 4 confers resistance to camptothecins. 2005 Nov 4
17 10220571 ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P. 1999 May 23
18 10378768 An enhanced active efflux of CPT-11 and SN-38 in cisplatin-resistant human KB carcinoma cells. 1999 Apr 26 2