benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

caspase 8 ; Homo sapiens







133 Article(s)
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1 35393392 N6-isopentenyladenosine induces cell death through necroptosis in human glioblastoma cells. 2022 Apr 7 3
2 33841010 20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades. 2021 Mar 2
3 34466155 Pioglitazone mediates apoptosis in Caki cells via downregulating c-FLIP(L) expression and reducing Bcl-2 protein stability. 2021 Oct 2
4 32145587 Disulfiram/copper markedly induced myeloma cell apoptosis through activation of JNK and intrinsic and extrinsic apoptosis pathways. 2020 Jun 4
5 32539919 Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells. 2020 Jun 1 2
6 33073770 Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. 2020 Nov 1 1
7 33108350 Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis. 2020 Dec 3 1
8 30556589 Chrysanthemulide A induces apoptosis through DR5 upregulation via JNK-mediated autophagosome accumulation in human osteosarcoma cells. 2019 Aug 2
9 30668391 Dioscin-6'-O-acetate inhibits lung cancer cell proliferation via inducing cell cycle arrest and caspase-dependent apoptosis. 2019 Feb 1
10 32186020 Effect of Yanggan Jiedu Sanjie formula on human hepatocellular carcinoma Bel-7402 cells. 2019 Feb 1
11 29128513 Dihydroartemisinin induced caspase-dependent apoptosis through inhibiting the specificity protein 1 pathway in hepatocellular carcinoma SK-Hep-1 cells. 2018 Jan 1 1
12 30008897 Metformin-induced apoptosis facilitates degradation of the cellular caspase 8 (FLICE)-like inhibitory protein through a caspase-dependent pathway in human renal cell carcinoma A498 cells. 2018 Aug 1
13 30107166 Luteolin induces caspase-dependent apoptosis via inhibiting the AKT/osteopontin pathway in human hepatocellular carcinoma SK-Hep-1 cells. 2018 Sep 15 1
14 26375985 A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation. 2016 Mar 1 1
15 26448608 Autophagy-Mediated Degradation of IAPs and c-FLIP(L) Potentiates Apoptosis Induced by Combination of TRAIL and Chal-24. 2016 May 1
16 26912071 Smac mimetic sensitizes renal cell carcinoma cells to interferon-α-induced apoptosis. 2016 May 28 1
17 27695262 Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells. 2016 Oct-Dec 1
18 27752362 Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells. 2016 1
19 25521557 AG4, a compound isolated from Radix Ardisiae Gigantifoliae, induces apoptosis in human nasopharyngeal cancer CNE cells through intrinsic and extrinsic apoptosis pathways. 2015 Mar 2
20 26043797 MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells. 2015 Aug 1
21 24337492 Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway. 2014 Feb 1
22 24398693 The C-terminal domain of the long form of cellular FLICE-inhibitory protein (c-FLIPL) inhibits the interaction of the caspase 8 prodomain with the receptor-interacting protein 1 (RIP1) death domain and regulates caspase 8-dependent nuclear factor κB (NF-κB) activation. 2014 Feb 14 1
23 24481288 Corosolic acid induces apoptotic cell death in HCT116 human colon cancer cells through a caspase-dependent pathway. 2014 Apr 2
24 24530510 Evaluation of cell viability and apoptosis in human amniotic fluid-derived stem cells with natural cryoprotectants. 2014 Apr 1
25 24973666 Involvement of autophagy in cordycepin-induced apoptosis in human prostate carcinoma LNCaP cells. 2014 Jul 1
26 25036678 Induction of apoptosis by 2,3-dehydrosilybin via a caspase-dependent pathway in human HeLa cells. 2014 2
27 25066322 G226, a novel epipolythiodioxopiperazine derivative, induces autophagy and caspase-dependent apoptosis in human breast cancer cells in vitro. 2014 Aug 1
28 25124618 Activation of JNK/p38 pathway is responsible for α-methyl-n-butylshikonin induced mitochondria-dependent apoptosis in SW620 human colorectal cancer cells. 2014 1
29 25196075 Antiproliferative potential of a novel parthenin analog P16 as evident by apoptosis accompanied by down-regulation of PI3K/AKT and ERK pathways in human acute lymphoblastic leukemia MOLT-4 cells. 2014 Oct 5 1
30 23338568 Tat-SmacN7 induces radiosensitization in cancer cells through the activation of caspases and induction of apoptosis. 2013 Mar 2
31 23408429 The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in breast cancer. 2013 Mar 29 1
32 23410748 Differential effects of caspase inhibitors on TNF-induced necroptosis. 2013 Mar 15 3
33 23708311 Combined treatment with verrucarin A and tumor necrosis factor-α sensitizes apoptosis by overexpression of nuclear factor-kappaB-mediated Fas. 2013 Sep 2
34 24039967 Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. 2013 1
35 21901386 Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis. 2012 May 2
36 22114764 Butein induces apoptosis and inhibits prostate tumor growth in vitro and in vivo. 2012 Jun 1 1
37 22159898 Mechanism of ziram-induced apoptosis in human T lymphocytes. 2012 Apr 1
38 22342732 Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo. 2012 May 1 1
39 22644571 Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. 2012 Aug 2
40 21082355 Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism. 2011 Feb 2
41 21282353 Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases. 2011 Apr 2
42 21341336 Corosolic acid triggers mitochondria and caspase-dependent apoptotic cell death in osteosarcoma MG-63 cells. 2011 Sep 1
43 21566207 Aminopeptidase-N/CD13 is a potential proapoptotic target in human myeloid tumor cells. 2011 Aug 1
44 20127023 KBH-A42, a histone deacetylase inhibitor, inhibits the growth of doxorubicin-resistant leukemia cells expressing P-glycoprotein. 2010 Mar 1
45 20136500 TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation. 2010 Sep 15 1
46 20195576 Temporal dynamics of receptor-induced apoptosis in an affinity microdevice. 2010 Aug 1
47 20372860 Activation of caspases and apoptosis in response to low-voltage electric pulses. 2010 May 1
48 20580860 Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors. 2010 Sep 2
49 20696207 Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. 2010 Nov 1
50 20878065 Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway. 2010 Nov 1