Sorafenib

caspase 8 ; Homo sapiens







11 Article(s)
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1 30066934 Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress‑related autophagy in hepatocellular carcinoma. 2018 Oct 1
2 28154184 Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma. 2017 Apr 21 1
3 26662956 Synergistic effect of fisetin combined with sorafenib in human cervical cancer HeLa cells through activation of death receptor-5 mediated caspase-8/caspase-3 and the mitochondria-dependent apoptotic pathway. 2016 May 2
4 29431086 Antitumoral Activity of Sorafenib in Hepatocellular Carcinoma: Effects on Cell Survival and Death Pathways, Cell Metabolism Reprogramming, and Nitrosative and Oxidative Stress. 2016 1
5 25687050 [Mechanisms of sorafenib induced NB4 cell apoptosis]. 2015 Feb 2
6 25738310 Sorafenib-irinotecan sequential therapy augmented the anti-tumor efficacy of monotherapy in hepatocellular carcinoma cells HepG2. 2015 1
7 24195809 A synthetic dsRNA, as a TLR3 pathwaysynergist, combined with sorafenib suppresses HCC in vitro and in vivo. 2013 Nov 6 1
8 22843888 HDAC inhibitors synergize antiproliferative effect of sorafenib in renal cell carcinoma cells. 2012 Aug 1
9 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1
10 18787411 Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. 2008 Oct 2
11 17909059 The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. 2007 Oct 1 2