Paclitaxel

caspase 8 ; Homo sapiens







43 Article(s)
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1 33985619 lncCRLA Enhanced Chemoresistance in Lung Adenocarcinoma That Underwent EpithelialMesenchymal Transition. 2022 Jan 31 5
2 34088893 Smac-mimetic enhances antitumor effect of standard chemotherapy in ovarian cancer models via Caspase 8-independent mechanism. 2021 Jun 4 1
3 34363313 The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner. 2021 Sep 2
4 34457060 Role of JNK activation in paclitaxel-induced apoptosis in human head and neck squamous cell carcinoma. 2021 Oct 1
5 34479917 Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. 2021 Sep-Oct 1
6 34660779 Synergistic Antiproliferative Effects of All-Trans Retinoic Acid and Paclitaxel on Autosomal Dominant Polycystic Kidney Disease Epithelial Cells. 2021 1
7 30229430 Synergistic Anticancer Effect of a Combination of Paclitaxel and 5-Demethylnobiletin Against Lung Cancer Cell Line In Vitro and In Vivo. 2019 Apr 1
8 31702036 ST3Gal3 confers paclitaxel‑mediated chemoresistance in ovarian cancer cells by attenuating caspase‑8/3 signaling. 2019 Nov 3
9 28534969 The Cdc2/Cdk1 inhibitor, purvalanol A, enhances the cytotoxic effects of taxol through Op18/stathmin in non-small cell lung cancer cells in vitro. 2017 Jul 1
10 29333445 Retrograde Activation of the Extrinsic Apoptotic Pathway in Spinal-Projecting Neurons after a Complete Spinal Cord Injury in Lampreys. 2017 1
11 27195913 Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src. 2016 Aug 28 6
12 27779649 Effect of curcumin and paclitaxel on breast carcinogenesis. 2016 Dec 1
13 23524581 BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling. 2014 Mar 13 2
14 24525192 Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3. 2014 Apr 25 1
15 25089613 Oxygen-carbon nanotubes as a chemotherapy sensitizer for paclitaxel in breast cancer treatment. 2014 1
16 25374178 Roles of the Bcl-2/Bax ratio, caspase-8 and 9 in resistance of breast cancer cells to paclitaxel. 2014 1
17 23534290 Biochemical effects of combined action of gamma-irradiation and paclitaxel on anaplastic thyroid cancer cells. 2013 Jan-Feb 1
18 24168763 Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. 2013 1
19 22019170 Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancer. 2011 Dec 2
20 19415457 Human beta-galactoside alpha-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity. 2009 Nov 5
21 19561399 Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells. 2009 Oct 31 4
22 19661300 Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells. 2009 Aug 1
23 19668227 Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. 2009 Oct 8 6
24 16051289 Enhancement of esculetin on Taxol-induced apoptosis in human hepatoma HepG2 cells. 2006 Jan 1 1
25 16231322 FHIT protein enhances paclitaxel-induced apoptosis in lung cancer cells. 2006 Apr 1 3
26 15809765 IFN-gamma enhances paclitaxel-induced apoptosis that is modulated by activation of caspases 8 and 3 with a concomitant down regulation of the AKT survival pathway in cultured human keratinocytes. 2005 May 3
27 15907983 Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells. 2005 Jul 1
28 16080463 Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel. 2005 May-Jun 1
29 16170023 Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein. 2005 Sep 1
30 15130763 Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs. 2004 May 15 1
31 15197489 Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells. 2004 Oct 1
32 15452117 Taxol induces caspase-10-dependent apoptosis. 2004 Dec 3 1
33 15492279 Blockade of paclitaxel-induced thymidine phosphorylase expression can accelerate apoptosis in human prostate cancer cells. 2004 Oct 15 2
34 12522001 Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells. 2003 May 1 1
35 12700660 Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop. 2003 Apr 17 1
36 11839682 Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. 2002 Feb 1
37 11222383 Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3. 2001 Mar 1 2
38 11410792 Proteasome inhibitor 1 enhances paclitaxel-induced apoptosis in human lung adenocarcinoma cell line. 2001 Jul-Aug 1
39 11600533 Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel. 2001 Oct 3
40 11716366 Inhibition of drug-induced Fas ligand transcription and apoptosis by Bcl-XL. 2001 Sep 1
41 11077039 Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4). 2000 Dec 1 2
42 10527889 A crucial role of caspase 3 and caspase 8 in paclitaxel-induced apoptosis. 1999 Jul 6
43 9633517 Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis. 1998 May 25 1