| 1 |
34363313 | The stressosome, a caspase-8-activating signalling complex assembled in response to cell stress in an ATG5-mediated manner. | 2021 Sep |
2 |
| 2 |
33194045 | Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells. | 2020 |
1 |
| 3 |
27993669 | Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs. | 2017 Mar |
1 |
| 4 |
26622554 | Caspase-dependent drug-induced apoptosis is regulated by cell surface sialylation in human B-cell lymphoma. | 2015 Aug |
1 |
| 5 |
23430060 | Induction of apoptosis through caspase-independent or caspase-9-dependent pathway in mouse and human osteosarcoma cells by a new nitroxyl spin-labeled derivative of podophyllotoxin. | 2013 Jun |
1 |
| 6 |
24436715 | Canine notochordal cell-secreted factors protect murine and human nucleus pulposus cells from apoptosis by inhibition of activated caspase-9 and caspase-3/7. | 2013 Oct |
1 |
| 7 |
23124518 | Etoposide sensitizes neuroblastoma cells expressing caspase 8 to TRAIL. | 2012 Jun 21 |
5 |
| 8 |
21468663 | Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. | 2011 Jul |
1 |
| 9 |
21801448 | Essential role of caspase-8 in p53/p73-dependent apoptosis induced by etoposide in head and neck carcinoma cells. | 2011 Jul 31 |
7 |
| 10 |
20416058 | Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL. | 2010 Apr 23 |
3 |
| 11 |
19549763 | Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells. | 2009 Sep |
6 |
| 12 |
17627812 | Interferon-gamma mediated up-regulation of caspase-8 sensitizes medulloblastoma cells to radio- and chemotherapy. | 2007 Aug |
1 |
| 13 |
17694514 | Drug-induced Myc-mediated apoptosis of cancer cells is inhibited by stress protein Hsp70. | 2007 Dec 15 |
1 |
| 14 |
16319070 | A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells. | 2006 Mar 10 |
1 |
| 15 |
16442262 | Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis. | 2006 Sep |
1 |
| 16 |
16722146 | Role of caspase 8 as a determinant in chemosensitivity of p53-mutated head and neck squamous cell carcinoma cell lines. | 2006 Mar |
1 |
| 17 |
15611097 | Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis. | 2005 Feb 18 |
1 |
| 18 |
15615731 | Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage. | 2005 Apr 1 |
1 |
| 19 |
15788689 | Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells. | 2005 Mar 15 |
1 |
| 20 |
16010441 | Acquisition of Fas resistance by Fas receptor mutation in a childhood B-precursor acute lymphoblastic leukemia cell line, MML-1. | 2005 Aug |
1 |
| 21 |
15161627 | Monitoring caspase activity in living cells using fluorescent proteins and flow cytometry. | 2004 Jun |
1 |
| 22 |
15254227 | Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. | 2004 Aug |
2 |
| 23 |
15262979 | Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. | 2004 Sep 24 |
3 |
| 24 |
15454884 | Nitric oxide acts on the mitochondria and protects human endothelial cells from apoptosis. | 2004 Sep |
1 |
| 25 |
12605597 | Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases. | 2003 May 1 |
1 |
| 26 |
12764618 | Immunofluorescent detection of activation of initiator caspases-8 and -9 during pharmacologically induced apoptosis of cultured HeLa and endothelial cells. | 2003 Jun |
1 |
| 27 |
12881712 | Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases. | 2003 Jul 17 |
1 |
| 28 |
14519653 | Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells. | 2003 Sep 15 |
1 |
| 29 |
11861801 | Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells). | 2002 Mar |
1 |
| 30 |
11604558 | Characteristics of etoposide-induced apoptotic cell death in the U-937 human lymphoma cell line. | 2001 Sep |
1 |
| 31 |
10749135 | The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis. | 2000 Mar 15 |
2 |
| 32 |
10194469 | Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis. | 1999 Apr |
1 |
| 33 |
10216102 | Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction. | 1999 May 1 |
1 |
| 34 |
10318846 | Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation. | 1999 May 14 |
1 |
| 35 |
10022243 | Release of mitochondrial cytochrome c is upstream of caspase activation in chemical-induced apoptosis in human monocytic tumour cells. | 1998 Dec 28 |
1 |
| 36 |
14646514 | The anti-cancer drug etoposide can induce caspase-8 processing and apoptosis in the absence of CD95 receptor-ligand interaction. | 1998 |
3 |