| 1 |
32418059 | Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosis. | 2020 Jun |
3 |
| 2 |
32712543 | The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. | 2020 Oct |
2 |
| 3 |
33194045 | Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells. | 2020 |
1 |
| 4 |
31369761 | The role of toll-like receptors in the protective effect of melatonin against doxorubicin-induced pancreatic beta cell toxicity. | 2019 Sep 15 |
1 |
| 5 |
28627658 | Shikonin promotes adriamycin‑induced apoptosis by upregulating caspase‑3 and caspase‑8 in osteosarcoma. | 2017 Aug |
1 |
| 6 |
28938593 | Endoplasmic reticulum stress-mediated membrane expression of CRT/ERp57 induces immunogenic apoptosis in drug-resistant endometrial cancer cells. | 2017 Aug 29 |
2 |
| 7 |
27278553 | Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines. | 2016 Aug |
2 |
| 8 |
26036637 | EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy. | 2015 Jul 10 |
2 |
| 9 |
26504757 | Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells. | 2015 Sep |
2 |
| 10 |
26745109 | Early Activation of Apoptosis and Caspase-independent Cell Death Plays an Important Role in Mediating the Cytotoxic and Genotoxic Effects of WP 631 in Ovarian Cancer Cells. | 2015 |
1 |
| 11 |
23504627 | Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling. | 2013 Oct 1 |
1 |
| 12 |
23647679 | Retaining cytotoxic activity of anthrapyridone CO1 against multidrug resistant cells is related to the ability to induce concomitantly apoptosis and lysosomal death of leukaemia HL60/VINC and HL60/DOX cells. | 2013 Jun |
1 |
| 13 |
22198116 | Anthraquinone antitumour agents, doxorubicin, pirarubicin and benzoperimidine BP1, trigger caspase-3/caspase-8-dependent apoptosis of leukaemia sensitive HL60 and resistant HL60/VINC and HL60/DOX cells. | 2012 Apr |
1 |
| 14 |
22609468 | Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: reactive oxygen species generation and inactive shortened SOD1 isoform implications. | 2012 Jun 25 |
1 |
| 15 |
21214929 | α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73. | 2011 Jan 7 |
1 |
| 16 |
21333751 | Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo. | 2011 Oct |
1 |
| 17 |
21536373 | Alpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin efflux. | 2011 Aug 28 |
2 |
| 18 |
21854868 | Fas/FasL-dependent and -independent activation of caspase-8 in doxorubicin-treated human breast cancer MCF-7 cells: ADAM10 down-regulation activates Fas/FasL signaling pathway. | 2011 Dec |
7 |
| 19 |
20416058 | Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL. | 2010 Apr 23 |
3 |
| 20 |
20512627 | N,N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF. | 2010 Aug |
1 |
| 21 |
19082486 | Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines. | 2009 Jan |
1 |
| 22 |
19625063 | Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins. | 2009 Sep |
1 |
| 23 |
20193325 | [Apoptosis in Jurkat cells induced by bortezomib combined with adriamycin]. | 2009 Dec |
1 |
| 24 |
18508926 | DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin. | 2008 Aug |
5 |
| 25 |
18728974 | Enhanced effect of IFNgamma on the induced apoptosis of neuroblastoma cells by cytotoxic drugs. | 2008 Sep |
1 |
| 26 |
17390070 | Caspase expression profile and functional activity in a panel of breast cancer cell lines. | 2007 May |
1 |
| 27 |
17437844 | Enhancement of death receptor 4 mediated apoptosis and cytotoxicity in renal cell carcinoma cells by subtoxic concentrations of doxorubicin. | 2007 May |
1 |
| 28 |
17627812 | Interferon-gamma mediated up-regulation of caspase-8 sensitizes medulloblastoma cells to radio- and chemotherapy. | 2007 Aug |
1 |
| 29 |
17922852 | Low concentrations of doxorubicin sensitizes human solid cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-receptor (R) 2-mediated apoptosis by inducing TRAIL-R2 expression. | 2007 Dec |
2 |
| 30 |
17970047 | Doxorubicin and selenium cooperatively induce fas signaling in the absence of Fas/Fas ligand interaction. | 2007 Sep-Oct |
1 |
| 31 |
18082045 | [5-azacytidine enhances anti-tumor efficacy of doxorubicin to neuroblastoma cell lines]. | 2007 Dec |
2 |
| 32 |
16483679 | A combined treatment TNF-alpha/doxorubicin alleviates the resistance of MCF-7/Adr cells to cytotoxic treatment. | 2006 Feb |
1 |
| 33 |
17013758 | Caspase-3 mediated feedback activation of apical caspases in doxorubicin and TNF-alpha induced apoptosis. | 2006 Nov |
1 |
| 34 |
15812552 | Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC cells. | 2005 Apr 25 |
1 |
| 35 |
15130763 | Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs. | 2004 May 15 |
1 |
| 36 |
15981920 | HPMA copolymer-bound doxorubicin induces apoptosis in human ovarian carcinoma cells by a Fas-independent pathway. | 2004 May-Jun |
3 |
| 37 |
12763223 | Trail-induced apoptosis and interaction with cytotoxic agents in soft tissue sarcoma cell lines. | 2003 Jun |
2 |
| 38 |
15033719 | Restoration of TRAIL-induced apoptosis in a caspase-8-deficient neuroblastoma cell line by stable re-expression of caspase-8. | 2003 Dec |
4 |
| 39 |
11948413 | IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. | 2002 Apr 4 |
1 |
| 40 |
11956588 | Doxorubicin enhances TRAIL-induced apoptosis in prostate cancer. | 2002 May |
1 |
| 41 |
12203125 | Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells. | 2002 Sep 5 |
3 |
| 42 |
11800021 | Doxorubicin-induced apoptosis in caspase-8-deficient neuroblastoma cells is mediated through direct action on mitochondria. | 2001 Dec |
4 |
| 43 |
10690508 | Molecular determinants of response to TRAIL in killing of normal and cancer cells. | 2000 Feb |
2 |
| 44 |
10802708 | Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. | 2000 May |
1 |
| 45 |
10216102 | Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction. | 1999 May 1 |
1 |
| 46 |
9766678 | Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. | 1998 Oct 1 |
2 |