Acetylcysteine

caspase 3 ; Rattus norvegicus







62 Article(s)
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1 35582415 N-acetylcysteine Ameliorates Vancomycin-induced Nephrotoxicity by Inhibiting Oxidative Stress and Apoptosis in the in vivo and in vitro Models. 2022 2
2 33247942 Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model. 2021 May 2
3 34601074 Synergistic neuroprotective effects of hyperbaric oxygen and N-acetylcysteine against traumatic spinal cord injury in rat. 2021 Dec 1
4 34753902 N-acetylcysteine supplementation did not reverse mitochondrial oxidative stress, apoptosis, and inflammation in the salivary glands of hyperglycemic rats. 2021 Nov 9 1
5 31699387 New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay. 2020 Jan 2
6 32438104 Protective Effect of N-Acetylcysteine Pretreatment on Acute Kidney Injury in Septic Rats. 2020 Oct 1
7 32549180 Zinc-dependent changes in oxidative and endoplasmic reticulum stress during cardiomyocyte hypoxia/reoxygenation. 2020 Oct 25 2
8 30387809 N-acetylcysteine alleviates H2O2-induced damage via regulating the redox status of intracellular antioxidants in H9c2 cells. 2019 Jan 1
9 30633982 N-acetylcysteine alleviates fluoride-induced testicular apoptosis by modulating IRE1α/JNK signaling and nuclear Nrf2 activation. 2019 Mar 1
10 30755039 N-acetylcysteine reduces glutamate-induced cytotoxicity to fibroblasts of rat supraspinatus tendons. 2019 Sep 1
11 31173782 Amelioration of fenitrothion induced oxidative DNA damage and inactivation of caspase-3 in the brain and spleen tissues of male rats by N-acetylcysteine. 2019 Aug 15 1
12 31392607 The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats. 2019 Oct 1
13 31401317 Molecular mechanisms of Cisplatin- induced placental toxicity and teratogenicity in rats and the ameliorating role of N-acetyl-cysteine. 2019 Oct 2
14 31432125 Proapoptotic effects of 2,5‑hexanedione on pheochromocytoma cells via oxidative injury. 2019 Oct 1
15 30504734 MicroRNA-21 abrogates palmitate-induced cardiomyocyte apoptosis through caspase-3/NF-κB signal pathways. 2018 Dec 1
16 26851769 Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia. 2016 Jul 1
17 27003169 Cadmium Activates Reactive Oxygen Species-dependent AKT/mTOR and Mitochondrial Apoptotic Pathways in Neuronal Cells. 2016 Feb 1
18 27010086 2,5-hexanedione induced apoptosis of rat bone marrow mesenchymal stem cells by reactive oxygen species. 2016 May 25 1
19 25776470 N-acetylcysteine relieves oxidative stress and protects hippocampus of rat from radiation-induced apoptosis by inhibiting caspase-3. 2015 Mar 3
20 24085626 Rosmarinic acid inhibits chemical hypoxia-induced cytotoxicity in primary cultured rat hepatocytes. 2014 Jul 1
21 23124986 Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro. 2013 Mar 2
22 23353834 Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy. 2013 Apr 15 1
23 23975535 Protective effects of N-acetylcysteine on 3, 4-methylenedioxymethamphetamine-induced neurotoxicity in male Sprague-Dawley rats. 2013 Dec 1
24 24397138 [Effects of N-acetylcysteine on apoptosis induced by myocardial ischemia reperfusion injury in rats' heart transplantation]. 2013 Oct 1
25 24489592 Andrographolide, a Novel NF- κ B Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade. 2013 1
26 25610275 The effects of erdosteine and N-acetylcysteine on apoptotic and antiapoptotic markers in pulmonary epithelial cells in sepsis. 2013 Oct 1
27 22131350 The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer. 2012 Feb 1
28 22166790 The role of mitochondria-mediated intrinsic death pathway in gingerdione derivative I6-induced neuronal apoptosis. 2012 Mar 2
29 22316545 [Protective effect of N-acetylcysteine against pneumocyte apoptosis during ischemia/reperfusion injury of lung in rats]. 2012 Feb 2
30 22326494 Perfluorooctane sulfonate induces apoptosis of cerebellar granule cells via a ROS-dependent protein kinase C signaling pathway. 2012 Jun 1
31 22336129 N-acetylcysteine attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. 2012 Aug 1
32 22420031 N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus. 2012 Apr 1
33 22714038 Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos. 2012 Sep 1 2
34 21242791 N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. 2011 Apr 1
35 21427628 Impact of N-acetylcysteine on neonatal cardiomyocyte ischemia-reperfusion injury. 2011 Jul 2
36 21721350 Immunohistochemical expression of apoptosis and VEGF expression on random skin flaps in rats treated with hyperbaric oxygen and N-acetylcysteine. 2011 May-Jun 1
37 21961969 Calcium overload induces C6 rat glioma cell apoptosis in sonodynamic therapy. 2011 Oct 2
38 19725096 N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis. 2010 Feb 1
39 19840221 N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy. 2010 Jan 1
40 20114059 Reduced cellular redox status induces 4-hydroxynonenal-mediated caspase 3 activation leading to erythrocyte death during chronic arsenic exposure in rats. 2010 May 1 2
41 20179891 [The protective mechanism of N-acetylcysteine against ischemia/reperfusion induced gastric injury in rats]. 2010 Feb 25 1
42 20356861 Effect of alpha-ketoglutarate and N-acetyl cysteine on cyanide-induced oxidative stress mediated cell death in PC12 cells. 2010 Jun 1
43 20525644 Mitochondrial uncoupling downregulates calsequestrin expression and reduces SR Ca2+ stores in cardiomyocytes. 2010 Oct 1 1
44 20824644 N-acetylcysteine counteracts oxidative stress and prevents hCG-induced apoptosis in rat Leydig cells through down regulation of caspase-8 and JNK. 2010 Oct 1
45 18791325 N-acetylcysteine-mediated antioxidation prevents hyperglycemia-induced apoptosis and collagen synthesis in rat mesangial cells. 2009 1
46 19559059 N-acetylcysteine alters apoptotic gene expression in axotomised primary sensory afferent subpopulations. 2009 Oct 2
47 19664398 [Protective effects and mechanism of N-acetylcysteine on cardiac injury induced by ischemia/reperfusion in diabetic rats]. 2009 Aug 2
48 18385389 The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats. 2008 Jul 1
49 18496137 Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release. 2008 Jun 1
50 17034987 Maternal diabetes in vivo and high glucose concentration in vitro increases apoptosis in rat embryos. 2007 Jan 1