Doxorubicin

caspase 3 ; Rattus norvegicus







113 Article(s)
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1 34766659 Biochemical and histological alterations of doxorubicin-induced neurotoxicity in rats: Protective role of luteolin. 2022 Mar 1
2 34962009 Cardioprotective effects of alpha-mangostin on doxorubicin-induced cardiotoxicity in rats. 2022 Jan 1
3 35149209 Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature. 2022 Apr 2
4 35559248 Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway. 2022 1
5 35571249 Endogenous Hydrogen Sulfide Persulfidates Caspase-3 at Cysteine 163 to Inhibit Doxorubicin-Induced Cardiomyocyte Apoptosis. 2022 2
6 33358696 Co-administration of Luteolin mitigated toxicity in rats' lungs associated with doxorubicin treatment. 2021 Jan 15 1
7 33529370 Alpha-lipoic acid may ameliorate testicular damage by targeting dox-induced altered antioxidant parameters, mitofusin-2 and apoptotic gene expression. 2021 Apr 1
8 33547742 Acylated ghrelin protects against doxorubicin-induced nephropathy by activating silent information regulator 1. 2021 Jun 1
9 33827303 Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis. 2021 Oct 1
10 33882726 Alamandine significantly reduces doxorubicin-induced cardiotoxicity in rats. 2021 Oct 1
11 34029952 Comparative study on beneficial effects of vitamins B and D in attenuating doxorubicin induced cardiotoxicity in rats: Emphasis on calcium homeostasis. 2021 Aug 1
12 34371291 The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats. 2021 Dec 1
13 34403065 Neuroprotective Potential of Berberine Against Doxorubicin-Induced Toxicity in Rat's Brain. 2021 Dec 1
14 34431122 The antioxidant and anti-apoptotic potential of Pleurotus eryngii extract and its chitosan-loaded nanoparticles against doxorubicin-induced testicular toxicity in male rats. 2021 Dec 4
15 34510376 Dose-Dependent Cardioprotective Effect of Hemin in Doxorubicin-Induced Cardiotoxicity Via Nrf-2/HO-1 and TLR-5/NF-κB/TNF-α Signaling Pathways. 2021 Dec 1
16 34587120 MSCs enhances the protective effects of valsartan on attenuating the doxorubicin-induced myocardial injury via AngII/NOX/ROS/MAPK signaling pathway. 2021 Sep 29 1
17 34653889 Hesperetin may alleviate the development of doxorubicin-induced pulmonary toxicity by decreasing oxidative stress and apoptosis in male rats. 2021 Dec 4
18 31811646 Doxorubicin-induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways. 2020 Apr 1
19 31833156 Involvement of Yes-associated protein 1 (YAP1) in doxorubicin-induced cytotoxicity in H9c2 cardiac cells. 2020 Mar 3
20 31853613 Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles. 2020 Apr 1
21 32142765 Modulatory effect of metformin on cardiotoxicity induced by doxorubicin via the MAPK and AMPK pathways. 2020 May 15 1
22 32388215 Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro. 2020 Jul 1
23 32394736 Thymoquinone is a protective agent that reduces the negative effects of doxorubicin in rat testis. 2020 Oct 2
24 32627270 Nimbolide prevents myocardial damage by regulating cardiac biomarkers, antioxidant level, and apoptosis signaling against doxorubicin-induced cardiotoxicity in rats. 2020 Jul 6 1
25 32652078 BAY60-2770 attenuates doxorubicin-induced cardiotoxicity by decreased oxidative stress and enhanced autophagy. 2020 Sep 1 1
26 33011199 Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation. 2020 Dec 15 1
27 33374365 Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway. 2020 Dec 24 1
28 30734091 Irbesartan suppresses cardiac toxicity induced by doxorubicin via regulating the p38-MAPK/NF-κB and TGF-β1 pathways. 2019 Jun 1
29 30827825 Deciphering the molecular mechanism during doxorubicin-mediated oxidative stress, apoptosis through Nrf2 and PGC-1α in a rat testicular milieu. 2019 Mar 2
30 30836069 β-Caryophyllene, a natural bicyclic sesquiterpene attenuates doxorubicin-induced chronic cardiotoxicity via activation of myocardial cannabinoid type-2 (CB2) receptors in rats. 2019 May 1 1
31 30977406 The protective and therapeutic effects of linalool against doxorubicin-induced cardiotoxicity in Wistar albino rats. 2019 Jul 1
32 31120912 68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity. 2019 1
33 31216443 β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study. 2019 Sep 5 1
34 31279781 Apigenin attenuates doxorubicin induced cardiotoxicity via reducing oxidative stress and apoptosis in male rats. 2019 Sep 1 1
35 31403269 Euterpe oleracea Mart. (Açai) Supplementation Attenuates Acute Doxorubicin-Induced Cardiotoxicity in Rats. 2019 1
36 31479835 A new thiocyanoacetamide (2-cyano-2-p-nitrophenyl-N-benzylthioamide) reduces doxorubicin-induced in vitro toxicity in Sertoli cells by decreasing apoptosis and autophagy. 2019 Dec 1
37 31545955 The anti-cancer drug doxorubicin induces substantial epigenetic changes in cultured cardiomyocytes. 2019 Nov 1 1
38 29085977 All-trans-retinoic acid ameliorates doxorubicin-induced cardiotoxicity: in vivo potential involvement of oxidative stress, inflammation, and apoptosis via caspase-3 and p53 down-expression. 2018 Jan 2
39 29321061 Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis. 2018 Jan 10 1
40 29403560 Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity. 2018 Jan 1
41 30025410 MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity. 2018 1
42 30351976 Protective effect of irbesartan against doxorubicin-induced nephrotoxicity in rats: implication of AMPK, PI3K/Akt, and mTOR signaling pathways. 2018 Dec 1
43 27421682 Protective effect of Gallic acid on doxorubicin-induced testicular and epididymal toxicity. 2017 May 1
44 27829271 Ginsenoside Rb1 Inhibits Doxorubicin-Triggered H9C2 Cell Apoptosis via Aryl Hydrocarbon Receptor. 2017 Mar 1 1
45 28159361 Enhanced-autophagy by exenatide mitigates doxorubicin-induced cardiotoxicity. 2017 Apr 1 1
46 28257823 Ameliorative effects of sildenafil and/or febuxostat on doxorubicin-induced nephrotoxicity in rats. 2017 Jun 15 2
47 28447737 17β-estradiol protects against doxorubicin-induced cardiotoxicity in male Sprague-Dawley rats by regulating NADPH oxidase and apoptosis genes. 2017 May 1
48 28710069 Vitamin C mitigates oxidative/nitrosative stress and inflammation in doxorubicin-induced cardiomyopathy. 2017 Oct 1 1
49 28780599 Liraglutide ameliorates cardiotoxicity induced by doxorubicin in rats through the Akt/GSK-3β signaling pathway. 2017 Nov 1
50 28785995 Allicin ameliorates doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis. 2017 Oct 1