Pravastatin

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







125 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33419165 Pravastatin Promotes Endothelial Colony-Forming Cell Function, Angiogenic Signaling and Protein Expression In Vitro. 2021 Jan 6 1
2 34011532 Negative Regulation of Human Hepatic Constitutive Androstane Receptor by Cholesterol Synthesis Inhibition: Role of Sterol Regulatory Element Binding Proteins. 2021 Aug 1
3 34425670 A Novel Splice Site Variant in the LDLRAP1 Gene Causes Familial Hypercholesterolemia 2021 Sep 1 1
4 29665658 Effect of the anti-IL-17 antibody on allergic inflammation in an obesity-related asthma model. 2018 Nov 1
5 26744986 Mixed effects of OATP1B1, BCRP and NTCP polymorphisms on the population pharmacokinetics of pravastatin in healthy volunteers. 2016 Sep 1
6 26222708 Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia. 2015 Sep 1
7 23907716 Co-medication of pravastatin and paroxetine-a categorical study. 2013 Nov 1
8 22216116 Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. 2011 1
9 19923996 HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study. 2010 Feb 1
10 19122443 [Effect of the brand and generic medicine of pravastatin on dyslipidemia in rabbits fed a high cholesterol diet]. 2009 Jan 2
11 20409966 A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study. 2009 Jul-Aug 1
12 17391675 Effect of pravastatin on the development of diabetes and adiponectin production. 2008 Jan 1
13 18383345 Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation. 2008 Jul 1
14 18797167 Chemoembolization combined with pravastatin improves survival in patients with hepatocellular carcinoma. 2008 1
15 17439540 SLCO1B1 521T-->C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients. 2007 Sep 1
16 17563401 Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients. 2007 Sep 2
17 16359930 Pharmacogenetics: progress, pitfalls and clinical potential for coronary heart disease. 2006 Feb 1
18 16603852 Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study. 2006 Apr 24 1
19 16327254 Lipids and stroke: the opportunity of lipid-lowering treatment. 2005 1
20 16356805 Improved outcome after acute coronary syndromes with an intensive versus standard lipid-lowering regimen: results from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) trial. 2005 Dec 1
21 15015196 Hydroxy-methylglutaryl-coenzyme A reductase inhibition improves endothelial dysfunction in type-1 diabetes. 2004 Apr 1
22 15116260 Pharmacogenetics of the CD14 endotoxin receptor polymorphism and progression of coronary atherosclerosis. 2004 May 1
23 15199031 Pharmacogenetic study of statin therapy and cholesterol reduction. 2004 Jun 16 1
24 15205608 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest. 2004 Jul 1
25 12733694 Effects of cholesterol-lowering therapy on pressor hyperreactivity to stress in hypercholesterolemic patients. 2003 Apr 1
26 11831546 Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus. 2002 Feb 1
27 11906972 Experimental model of escape phenomenon in hamsters and the effectiveness of YM-53601 in the model. 2002 Mar 1
28 12032266 A randomized crossover trial of combination pharmacologic therapy in children with familial hyperlipidemia. 2002 Jun 1
29 12039487 Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin. 2002 Jun 5 1
30 12433810 Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. 2002 Dec 1
31 12459073 [Comparative study of the impact of diet versus pravastatin on color vision in Brodman area 19 detected by computerized chromatic analysis (CARDIOCOLOUR Study)]. 2002 Dec 1
32 12652117 Massive postoperative rhabdomyolysis following combined CABG/abdominal aortic replacement: a possible association with HMG-CoA reductase inhibitors. 2002 Sep 1
33 11165421 Operational aspects of terminating the doxazosin arm of The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). 2001 Feb 1
34 11244205 Advantages of lipid-lowering therapy in cerebral ischemia: role of HMG-CoA reductase inhibitors. 2001 1
35 11276395 Recent clinical trial highlights in hypertension. 2001 Apr 1
36 11318529 Role of fibrates and HMG-CoA reductase inhibitors in gallstone formation: epidemiological study in an unselected population. 2001 Mar 1
37 11356905 Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. 2001 Jun 1
38 11359999 The in vitro inhibitory effect of tannin derivatives on 3-hydroxy-3-methylglutaryl-coenzyme a reductase on vero cells. 2001 May 1
39 11404165 Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients. 2001 Jun 1
40 11469968 Hyperlipidemia in Chronic Cholestatic Liver Disease. 2001 Apr 1
41 11602546 Pravastatin and endothelium dependent vasomotion after coronary angioplasty: the PREFACE trial. 2001 Nov 1
42 15989499 The effect of HMG-CoA reductase inhibitors on chronic allograft rejection. 2001 Apr 1
43 10732240 [Intensification in vivo of free radical oxidation of low density lipoproteins in plasma from patients with myocardial ischemia treated by HMG-CoA-reductase pravastatin and suppression of lipid peroxidation by ubiquinone Q10]. 2000 Feb 1
44 10952477 Effect of fluconazole on plasma fluvastatin and pravastatin concentrations. 2000 Jun 1
45 11030795 Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. 2000 Oct 1
46 11074211 Development of tachyphylaxis among patients taking HMG CoA reductase inhibitors. 2000 Nov 15 1
47 10381291 Metabolic basis of high density lipoproteins and apolipoprotein A-I increase by HMG-CoA reductase inhibition in healthy subjects and a patient with coronary artery disease. 1999 May 1
48 10399998 Pravastatin prevents clinical events in revascularized patients with average cholesterol concentrations. Cholesterol and Recurrent Events CARE Investigators. 1999 Jul 1
49 10490896 Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin. 1999 Oct 1
50 10554675 Prevention of mortality from coronary heart disease with pravastatin. 1999 Oct 1