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30282717 | The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs. | 2019 Jan 1 |
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28455498 | Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner. | 2017 Apr 28 |
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26286913 | SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor. | 2015 Dec 15 |
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23460737 | GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. | 2013 Apr 1 |
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24098653 | High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28. | 2013 |
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24105423 | Conformational change of Sos-derived proline-rich peptide upon binding Grb2 N-terminal SH3 domain probed by NMR. | 2013 Oct 9 |
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22253690 | Modeling of molecular interaction between apoptin, BCR-Abl and CrkL--an alternative approach to conventional rational drug design. | 2012 |
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21508312 | GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration. | 2011 Jun 15 |
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| 9 |
21745501 | HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction. | 2011 Oct |
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20554525 | Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growth. | 2010 Aug 20 |
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20643654 | PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival. | 2010 Sep 17 |
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19109251 | Distinct recruitment of Eps15 via Its coiled-coil domain is required for efficient down-regulation of the met receptor tyrosine kinase. | 2009 Mar 27 |
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19509291 | GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signaling. | 2009 Jul 24 |
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19815557 | Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling. | 2009 Dec 11 |
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| 15 |
18620523 | Grb2 signaling in cell motility and cancer. | 2008 Aug |
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| 16 |
18778683 | Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1. | 2008 Nov 1 |
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| 17 |
18789888 | The adaptor protein Grb2 regulates cell surface Fas ligand in Schwann cells. | 2008 Nov 14 |
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| 18 |
17113302 | High affinity Grb2-SH3 domain ligand incorporating Cbeta-substituted prolines in a Sos-derived decapeptide. | 2007 Feb 1 |
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| 19 |
17869481 | A non-canonical Grb2-PLC-gamma1-Sos cascade triggered by lipovitellin 1, an apolipoprotein B homologue. | 2007 Dec |
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| 20 |
16480678 | Affinity chromatography for purification of the modular protein growth factor receptor-bound protein 2 and development of a screening test for growth factor receptor-bound protein 2 Src homology 3 domain inhibitor using peroxidase-linked ligand. | 2006 Apr 1 |
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16520382 | Sos-mediated activation of rac1 by p66shc. | 2006 Mar 13 |
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16893902 | A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation. | 2006 Oct 6 |
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| 23 |
16906159 | Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1. | 2006 Sep |
2 |
| 24 |
15486046 | Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. | 2005 Feb |
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| 25 |
14679214 | A novel proteomic screen for peptide-protein interactions. | 2004 Mar 12 |
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| 26 |
12522133 | p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling. | 2003 Mar 14 |
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| 27 |
12839496 | Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation. | 2003 Aug |
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| 28 |
11964172 | Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement. | 2002 May 1 |
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| 29 |
12399475 | Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre. | 2002 Dec 27 |
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| 30 |
11178911 | Solution structure of Grb2 reveals extensive flexibility necessary for target recognition. | 2001 Feb 23 |
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11278754 | Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1. | 2001 Apr 13 |
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| 32 |
11353842 | Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. | 2001 May 22 |
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11371563 | The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2. | 2001 Jul 27 |
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| 34 |
11509578 | mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation. | 2001 Oct 19 |
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| 35 |
11533253 | Recruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2. | 2001 Oct |
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| 36 |
11726515 | Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling. | 2001 Dec 3 |
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| 37 |
11746524 | Grb2 dominantly associates with dynamin II in human hepatocellular carcinoma HepG2 cells. | 2001 |
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| 38 |
11878897 | The small 11-kDa protein from B19 parvovirus binds growth factor receptor-binding protein 2 in vitro in a Src homology 3 domain/ligand-dependent manner. | 2001 Dec 20 |
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| 39 |
10636929 | Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. | 2000 Jan 21 |
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| 40 |
10747847 | Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. | 2000 May 5 |
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| 41 |
10749687 | Involvement of proline-rich tyrosine kinase 2 in platelet activation: tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2. | 2000 Apr 15 |
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| 42 |
10869177 | Circular dichroic investigation of the native and non-native conformational states of the growth factor receptor-binding protein 2 N-terminal src homology domain 3: effect of binding to a proline-rich peptide from guanine nucleotide exchange factor. | 2000 Jul 4 |
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| 43 |
10903901 | Characterization of the beta-dystroglycan-growth factor receptor 2 (Grb2) interaction. | 2000 Jul 21 |
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| 44 |
11007954 | Inhibitors of Ras signal transduction as antitumor agents. | 2000 Oct 15 |
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| 45 |
9891069 | Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase. | 1999 Feb |
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| 46 |
10393272 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins. | 1999 Jul 6 |
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| 47 |
10395825 | Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin. | 1999 Jul 16 |
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| 48 |
12054111 | Insulin and EGF receptors integrate the Ras and Rap signaling pathways. | 1999 Mar |
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| 49 |
9452513 | Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides. | 1998 Feb 6 |
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| 50 |
9484780 | Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins. | 1998 Feb 19 |
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