| 1 |
33314682 | The PKM2 activator TEPP-46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF-1α accumulation. | 2021 May |
2 |
| 2 |
34156680 | The PKM2 activator TEPP-46 attenuates MCD feeding-induced nonalcoholic steatohepatitis by inhibiting the activation of Kupffer cells. | 2021 Jun |
6 |
| 3 |
34798593 | Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia. | 2021 Dec |
1 |
| 4 |
32198052 | Nuclear accumulation of pyruvate kinase M2 promotes liver regeneration via activation of signal transducer and activator of transcription 3. | 2020 Jun 1 |
1 |
| 5 |
32323562 | PKM2 Activator TEPP-46 Attenuates Thoracic Aortic Aneurysm and Dissection by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion. | 2020 Jul |
2 |
| 6 |
32719938 | Pyruvate kinase M2 activation protects against the proliferation and migration of pulmonary artery smooth muscle cells. | 2020 Dec |
1 |
| 7 |
33061637 | Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis. | 2020 |
2 |
| 8 |
33131100 | Sirtuin 3 governs autophagy-dependent glycolysis during Angiotensin II-induced endothelial-to-mesenchymal transition. | 2020 Dec |
1 |
| 9 |
33542713 | Activator-Mediated Pyruvate Kinase M2 Activation Contributes to Endotoxin Tolerance by Promoting Mitochondrial Biogenesis. | 2020 |
4 |
| 10 |
29552018 | Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2-Signal Transducer and Activator of Transcription 3 Pathway. | 2018 |
1 |
| 11 |
28436957 | Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. | 2017 Jun |
2 |
| 12 |
23905203 | ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model | 2010 |
2 |