Cholesterol

low density lipoprotein receptor ; Homo sapiens







1191 Article(s)
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1 33980760 Effectiveness and Safety of Lipid-Lowering Drug Treatments in Japanese Patients with Familial Hypercholesterolemia: Familial Hypercholesterolemia Expert Forum (FAME) Study. 2022 May 1 1
2 34374964 The Differential Metabolomes in Cumulus and Mural Granulosa Cells from Human Preovulatory Follicles. 2022 Apr 1
3 34809444 Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome. 2022 Jan 7 3
4 34809446 PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease. 2022 Jan 1
5 34846648 A novel low-density lipoprotein receptor variant in a Ukrainian patient: a case report and overview of the disease-causing low-density lipoprotein receptor variants associated to familial hypercholesterolemia. 2022 Feb 1
6 34871818 Genetic mutations, regression of Achilles tendon thickness, and cardiovascular events among patients with familial hypercholesterolemia. 2022 Jan 1
7 35007650 Associations of pro-protein convertase subtilisin-like kexin type 9, soluble low-density lipoprotein receptor and coronary artery disease: A case-control study. 2022 Mar 1 3
8 35123858 Search for familial hypercholesterolemia patients in an Italian community: A real-life retrospective study. 2022 Mar 2
9 35140212 Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. 2022 Feb 9 1
10 35162992 Emerging Insights on the Diverse Roles of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Chronic Liver Diseases: Cholesterol Metabolism and Beyond. 2022 Jan 19 1
11 35181275 Clinical decision support for familial hypercholesterolemia (CDS-FH): Rationale and design of a cluster randomized trial in primary care. 2022 May 1
12 35221836 Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management. 2022 1
13 35276852 Assessment of the Cholesterol-Lowering Effect of MOMAST®: Biochemical and Cellular Studies. 2022 Jan 23 1
14 35323658 The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases. 2022 Feb 26 2
15 35336039 Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity. 2022 Mar 18 2
16 35386468 Black TiO2 nanoprobe-mediated mild phototherapy reduces intracellular lipid levels in atherosclerotic foam cells via cholesterol regulation pathways instead of apoptosis. 2022 Nov 2
17 35390434 Genetic variation and intestinal cholesterol absorption in humans: A systematic review and a gene network analysis. 2022 Apr 1
18 35409162 The Activity of Ten Natural Extracts Combined in a Unique Blend to Maintain Cholesterol Homeostasis-In Vitro Model. 2022 Mar 30 1
19 35409167 Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches. 2022 Mar 30 2
20 35429393 Motivating cascade testing for familial hypercholesterolemia: applying the extended parallel process model for clinician communication. 2022 Apr 16 1
21 35432976 Daily intake of up to two eggs for 11 weeks does not affect the cholesterol balance of Chinese young adults. 2022 Apr 1
22 35447021 No association between LDL receptor and CETP genetic variants and atorvastatin response in Jordanian hyperlipidemic patients. 2022 Apr 21 2
23 35467154 An update on lipid apheresis for familial hypercholesterolemia. 2022 Apr 25 2
24 35469449 Lessons learned from the evinacumab trials in the treatment of homozygous familial hypercholesterolemia. 2022 Jun 1
25 35493299 Cholesterol Metabolic Markers for Differential Evaluation of Patients with Hyperlipidemia and Familial Hypercholesterolemia. 2022 5
26 35527125 What characterizes event-free elderly FH patients? A comprehensive lipoprotein profiling. 2022 Jul 1
27 35533584 Expression patterns of genes in steroidogenic, cholesterol uptake, and liver x receptor-mediated cholesterol efflux pathway regulating cholesterol homeostasis in natural and PGF2α induced luteolysis as well as early pregnancy in ovine corpus luteum. 2022 May 1
28 35565772 Hempseed (Cannabis sativa) Peptide H3 (IGFLIIWV) Exerts Cholesterol-Lowering Effects in Human Hepatic Cell Line. 2022 Apr 26 1
29 35585420 Retinoic acid increases the cellular cholesterol predominantly in a mTOR-independent manner. 2022 May 18 2
30 35599686 Testosterone Deficiency Promotes Hypercholesteremia and Attenuates Cholesterol Liver Uptake via AR/PCSK9/LDLR Pathways. 2022 1
31 32090592 Are anti-inflammatory agents and nutraceuticals - novel inhibitors of PCSK9? 2021 2
32 32875580 Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall. 2021 Apr 2
33 32991689 PCSK9 and LRP5 in macrophage lipid internalization and inflammation. 2021 Jul 27 3
34 33147992 Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town. 2021 Feb 1
35 33222314 PCSK9 inhibitors for COVID-19: an opportunity to enhance the antiviral action of interferon in patients with hypercholesterolaemia. 2021 May 1
36 33307067 PCSK9: Associated with cardiac diseases and their risk factors? 2021 Jun 15 1
37 33315477 Lifelong Reduction in LDL (Low-Density Lipoprotein) Cholesterol due to a Gain-of-Function Mutation in LDLR. 2021 Feb 6
38 33342622 The Effect of Statins in Children and Adolescents With Familial Hypercholesterolemia: A Systematic Review. 2021 May-Jun 1
39 33394716 Recent insights into low-density lipoprotein metabolism and therapy. 2021 Mar 1 1
40 33461934 Prognostic impact of cascade screening for familial hypercholesterolemia on cardiovascular events. 2021 Mar-Apr 2
41 33497862 LDL-cholesterol lowering and clinical outcomes in hypercholesterolemic subjects with and without a familial hypercholesterolemia phenotype: Analysis from the secondary prevention 4S trial. 2021 Mar 1
42 33512150 Engineered EGF-A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). 2021 Feb 19 1
43 33513160 Genome-scale CRISPR screening for modifiers of cellular LDL uptake. 2021 Jan 1
44 33515402 Patterns and tempo of PCSK9 pseudogenizations suggest an ancient divergence in mammalian cholesterol homeostasis mechanisms. 2021 Feb 1
45 33515861 On the possible existence of a liver LDL-ostat, and its malfunctioning in familial hypercholesterolemia. 2021 Feb 3
46 33548684 The polarized localization of lipoprotein receptors and cholesterol transporters in the syncytiotrophoblast of the placenta is reproducible in a monolayer of primary human trophoblasts. 2021 Feb 2
47 33606190 Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling. 2021 Apr 3
48 33647772 Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy. 2021 Mar 2
49 33716107 Existing and emerging therapies for the treatment of familial hypercholesterolemia. 2021 4
50 33757439 Hepatic expression of cholesterol regulating genes favour increased circulating low-density lipoprotein in HIV infected patients with gallstone disease: a preliminary study. 2021 Mar 23 1