Cysteine

low density lipoprotein receptor ; Homo sapiens







46 Article(s)
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Pub. Year
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1 30332439 Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition. 2018 2
2 26529358 Identification of a homozygous missense mutation in LRP2 and a hemizygous missense mutation in TSPYL2 in a family with mild intellectual disability. 2016 Apr 1
3 25545329 Activity-associated effect of LDL receptor missense variants located in the cysteine-rich repeats. 2015 Feb 3
4 26195630 Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. 2015 Sep 18 1
5 24472543 L-Cysteine-induced up-regulation of the low-density lipoprotein receptor is mediated via a transforming growth factor-alpha signalling pathway. 2014 Feb 14 4
6 23105118 The M2 module of the Cys-His-rich domain (CHRD) of PCSK9 protein is needed for the extracellular low-density lipoprotein receptor (LDLR) degradation pathway. 2012 Dec 21 2
7 17461796 The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. 2007 Jun 1
8 16425180 Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1. 2006 Apr 1 2
9 12493918 Coordinated nonvectorial folding in a newly synthesized multidomain protein. 2002 Dec 20 2
10 11478865 NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor. 2001 Aug 10 1
11 10889196 Vesicle-reconstituted low density lipoprotein receptor. Visualization by cryoelectron microscopy. 2000 Sep 29 4
12 10924730 FH-Freiburg: a novel missense mutation (C317Y) in growth factor repeat A of the low density lipoprotein receptor gene in a German patient with homozygous familial hypercholesterolemia. 2000 Aug 1
13 9925662 The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. 1999 Feb 1
14 10235090 Low-density lipoprotein cholesterol bulk is the pivotal determinant of atherosclerosis in familial hypercholesterolemia. 1999 May 1 1
15 10318830 NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein. 1999 May 14 2
16 10508213 Identification and characterization of LRP8 (apoER2) in human blood platelets. 1999 Oct 1
17 9484237 Calcium is essential for the structural integrity of the cysteine-rich, ligand-binding repeat of the low-density lipoprotein receptor. 1998 Feb 10 2
18 9538514 Two novel slavic point mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia from St. Petersburg, Russia. 1998 Jan 1
19 9548597 Apolipoprotein E2 (Arg136 --> Cys) mutation in the receptor binding domain of apoE is not associated with dominant type III hyperlipoproteinemia. 1998 Mar 2
20 9573218 Characterization of determinants for envelope binding and infection in tva, the subgroup A avian sarcoma and leukosis virus receptor. 1998 Jun 2
21 9671701 Conversion of a human low-density lipoprotein receptor ligandbinding repeat to a virus receptor: identification of residues important for ligand specificity. 1998 Jul 21 2
22 9760226 Possible arrangement of the five domains in human complement factor I as determined by a combination of X-ray and neutron scattering and homology modeling. 1998 Oct 6 2
23 9262405 Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module. 1997 Aug 14 1
24 8655135 Malignant familial hypertrophic cardiomyopathy in a family with a 453Arg-->Cys mutation in the beta-myosin heavy chain gene: coexistence of sudden death and end-stage heart failure. 1996 May 1
25 8706711 A deletion in the first cysteine-rich repeat of the low-density-lipoprotein receptor leads to the formation of multiple misfolded isomers. 1996 Jul 1 2
26 8828968 Genetic diagnosis of familial hypercholesterolemia in affected relatives using pedigree tracing. 1996 Aug 2
27 8919878 Chiloscyllium plagiosum low-density lipoprotein receptor: evolutionary conservation of five different functional domains. 1996 Feb 2
28 7548065 Disulfide bridges of a cysteine-rich repeat of the LDL receptor ligand-binding domain. 1995 Oct 10 1
29 7578052 Three-dimensional structure of the second cysteine-rich repeat from the human low-density lipoprotein receptor. 1995 Nov 7 2
30 7603991 Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor. 1995 Jul 3 1
31 8558079 Molecular characterization of two monoclonal antibodies specific for the LDL receptor-binding site of human apolipoprotein E. 1995 Sep 1
32 7981713 Characterization of a disease-causing Glu119-Lys mutation in the low-density lipoprotein receptor gene in two Danish families with heterozygous familial hypercholesterolemia. 1994 1
33 8514788 Linker chain L1 of earthworm hemoglobin. Structure of gene and protein: homology with low density lipoprotein receptor. 1993 Jun 25 2
34 1863993 DNA deletions in the low density lipoprotein (LDL) receptor gene in Danish families with familial hypercholesterolemia. 1991 Jun 1
35 2352257 An exon 4 mutation identified in the majority of South African familial hypercholesterolaemics. 1990 May 3
36 2597675 Structure of the low-density lipoprotein receptor-related protein (LRP) promoter. 1989 Dec 22 1
37 2789218 The molecular architecture of human complement component C6. 1989 Sep 25 1
38 2901412 Transport-deficient mutations in the low density lipoprotein receptor. Alterations in the cysteine-rich and cysteine-poor regions of the protein block intracellular transport. 1988 Sep 15 2
39 3263645 Deletion in the first cysteine-rich repeat of low density lipoprotein receptor impairs its transport but not lipoprotein binding in fibroblasts from a subject with familial hypercholesterolemia. 1988 Nov 2
40 3335508 The structure of human complement component C7 and the C5b-7 complex. 1988 Jan 5 1
41 3320043 First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins. 1987 Dec 25 2
42 3498887 Inhibition of the lytic activity of perforin (cytolysin) and of late complement components by proteoglycans. 1987 Sep 1
43 3571247 Taurine enhances low density lipoprotein binding. Internalization and degradation by cultured Hep G2 cells. 1987 May 5 2
44 2424021 Antigenic crossreactivity of the alpha subunit of complement component C8 with the cysteine-rich domain shared by complement component C9 and low density lipoprotein receptor. 1986 Jun 1
45 2427933 A mechanism for the insertion of complement component C9 into target membranes. 1986 May 1
46 3020025 Deletion of exon encoding cysteine-rich repeat of low density lipoprotein receptor alters its binding specificity in a subject with familial hypercholesterolemia. 1986 Oct 5 2