| 1 |
33787846 | Synergy and allostery in ligand binding by HIV-1 Nef. | 2021 Apr 30 |
1 |
| 2 |
26927806 | Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays. | 2016 Mar 1 |
1 |
| 3 |
24051604 | HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon. | 2013 Sep 18 |
1 |
| 4 |
22407921 | HIV-1 proteins preferentially activate anti-inflammatory M2-type macrophages. | 2012 Apr 15 |
1 |
| 5 |
22537596 | Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. | 2012 Apr 27 |
3 |
| 6 |
22651890 | Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. | 2012 May 31 |
3 |
| 7 |
22705789 | Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. | 2012 Jun 17 |
2 |
| 8 |
21093412 | Naturally arising HIV-1 Nef variants conferring escape from cytotoxic T lymphocytes influence viral entry co-receptor expression and susceptibility to superinfection. | 2010 Dec 17 |
3 |
| 9 |
18178851 | CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef. | 2008 Jan 15 |
1 |
| 10 |
18707241 | The proline-rich region of HIV-1 Nef affects CXCR4-mediated chemotaxis in Jurkat T cells. | 2008 Sep |
1 |
| 11 |
18799583 | Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism. | 2008 Dec |
1 |
| 12 |
15976924 | Mapping the binding site of full length HIV-1 Nef on human Lck SH3 by NMR spectroscopy. | 2005 |
1 |
| 13 |
16043695 | HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. | 2005 Aug 2 |
1 |
| 14 |
11525746 | A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells. | 2001 Aug 21 |
1 |
| 15 |
10660579 | HIV-2 and SIV nef proteins target different Src family SH3 domains than does HIV-1 Nef because of a triple amino acid substitution. | 2000 Feb 11 |
1 |
| 16 |
10807905 | The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation. | 2000 Jul 28 |
2 |
| 17 |
9971776 | Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking. | 1999 Mar |
3 |
| 18 |
10388555 | Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events. | 1999 Jul 2 |
2 |
| 19 |
9705913 | The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism. | 1998 Aug 1 |
2 |
| 20 |
9218412 | SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1. | 1997 Jul 18 |
2 |
| 21 |
9288906 | Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization. | 1997 Aug 1 |
3 |
| 22 |
9351809 | The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. | 1997 Oct 15 |
1 |
| 23 |
8626429 | Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects. | 1996 Mar 15 |
1 |
| 24 |
8794306 | Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity. | 1996 Oct |
3 |
| 25 |
8862424 | HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. | 1996 Oct 1 |
4 |