Protein Name apolipoprotein L1
Organism Homo sapiens
Gene ID 8542
Gene Symbol

APOL1

UniProt O14791 (APOL1_HUMAN), B1AH95 (B1AH95_HUMAN), Q2KHQ6 (Q2KHQ6_HUMAN)
Relationships Total Number of functionally related compound(s) : 84
Total Number of Articles : 78
Description

apolipoprotein L1

Gene Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

synonyms
  • apolipoprotein L1
  • apolipoprotein L 1
  • apolipoprotein L1-B3
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Properties