Protein Name TNF superfamily member 4
Organism Homo sapiens
Gene ID 7292
Gene Symbol

TNFSF4

UniProt P23510 (TNFL4_HUMAN), A0A024R937 (A0A024R937_HUMAN)
Relationships Total Number of functionally related compound(s) : 61
Total Number of Articles : 59
Description

TNF superfamily member 4

Gene Summary

This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

synonyms
  • tumor necrosis factor ligand superfamily member 4
  • CD134 ligand
  • OX40 antigen ligand
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Properties