Protein Name CREB binding protein
Organism Rattus norvegicus
Gene ID 54244
Gene Symbol

Crebbp

UniProt F1M9G7 (F1M9G7_RAT)
Relationships Total Number of functionally related compound(s) : 75
Total Number of Articles : 79
Description

CREB binding protein

Gene Summary

Enables several functions, including SMAD binding activity; peroxisome proliferator activated receptor binding activity; and transcription coactivator binding activity. Involved in several processes, including behavioral response to cocaine; long-term memory; and positive regulation of cell adhesion molecule production. Located in nuclear body. Part of transcription regulator complex. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; acute lymphoblastic leukemia; and acute myeloid leukemia. Orthologous to human CREBBP (CREB binding protein). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • histone lysine acetyltransferase CREBBP
  • protein lactyltransferas CREBBP
  • protein-lysine acetyltransferase CREBBP
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Properties