Protein Name pyrroline-5-carboxylate reductase 1
Organism Homo sapiens
Gene ID 5831
Gene Symbol

PYCR1

UniProt P32322 (P5CR1_HUMAN), E2QRB3 (E2QRB3_HUMAN), J3QL32 (J3QL32_HUMAN), A0A024R8U9 (A0A024R8U9_HUMAN), Q8TBX0 (Q8TBX0_HUMAN)
Relationships Total Number of functionally related compound(s) : 135
Total Number of Articles : 138
Description

pyrroline-5-carboxylate reductase 1

Gene Summary

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

synonyms
  • pyrroline-5-carboxylate reductase 1, mitochondrial
  • P5C reductase 1
  • proliferation-inducing protein 45
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Properties