Protein Name | Bruton tyrosine kinase |
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Organism | Drosophila melanogaster |
Gene ID | 34132 |
Gene Symbol | Btk |
UniProt | P08630 (BTKL_DROME), M9PCD8 (M9PCD8_DROME), M9PCX8 (M9PCX8_DROME) |
Relationships |
Total Number of functionally related compound(s) :
7
Total Number of Articles : 7 |
Description |
Bruton tyrosine kinase |
Gene Summary |
Enables protein tyrosine kinase activity. Involved in several processes, including DNA endoreduplication; head involution; and oogenesis. Located in several cellular components, including apical part of cell; germline ring canal; and plasma membrane. Is expressed in several structures, including epithelium; extended germ band embryo; germ layer; reproductive system; and stage 5 embryo. Human ortholog(s) of this gene implicated in agammaglobulinemia (multiple); isolated growth hormone deficiency type III; lymphoma (multiple); and lymphoproliferative syndrome 1. Orthologous to several human genes including TEC (tec protein tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022] |
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