Protein Name phosphoribosyl pyrophosphate synthetase 1
Organism Rattus norvegicus
Gene ID 29562
Gene Symbol

Prps1

UniProt P60892 (PRPS1_RAT)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 4
Description

phosphoribosyl pyrophosphate synthetase 1

Gene Summary

Enables several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process; AMP biosynthetic process; and animal organ regeneration. Part of ribose phosphate diphosphokinase complex. Human ortholog(s) of this gene implicated in Arts syndrome; X-linked deafness 1; X-linked recessive disease (multiple); gout; and retinitis pigmentosa. Orthologous to human PRPS1 (phosphoribosyl pyrophosphate synthetase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ribose-phosphate pyrophosphokinase 1
  • PRS-I
  • phosphoribosyl pyrophosphate synthase I
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Properties