Protein Name choline O-acetyltransferase
Organism Rattus norvegicus
Gene ID 290567
Gene Symbol


UniProt A0A0G2JYQ6 (A0A0G2JYQ6_RAT)
Relationships Total Number of functionally related compound(s) : 358
Total Number of Articles : 572

choline O-acetyltransferase

Gene Summary

Enables choline O-acetyltransferase activity and choline binding activity. Involved in several processes, including acetylcholine biosynthetic process; antral ovarian follicle growth; and response to ethanol. Located in neuron projection. Biomarker of Alzheimer's disease and asthma. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Orthologous to human CHAT (choline O-acetyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

  • choline O-acetyltransferase
  • CHOACTase
  • choline acetylase
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