Protein Name Eukaryotic translation initiation factor 4E-2
Organism Caenorhabditis elegans
Gene ID 180393
Gene Symbol

ife-2

UniProt Q21693 (IF4E2_CAEEL)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 2
Description

Eukaryotic translation initiation factor 4E-2

Gene Summary

Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of response to oxidative stress; and positive regulation of translation. Located in cytoplasmic stress granule. Is expressed in several structures, including excretory canal; germ line; nerve ring; neurons; and vulva. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Eukaryotic translation initiation factor 4E-2
  • CELE_R04A9.4
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Properties