Protein Name Prolyl 4-hydroxylase subunit alpha-1
Organism Caenorhabditis elegans
Gene ID 176569
Gene Symbol

dpy-18

UniProt Q10576 (P4HA1_CAEEL)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

Prolyl 4-hydroxylase subunit alpha-1

Gene Summary

Enables procollagen-proline 4-dioxygenase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; embryo development; and embryonic body morphogenesis. Located in endoplasmic reticulum. Is expressed in hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in myopia. Orthologous to human P4HA1 (prolyl 4-hydroxylase subunit alpha 1) and P4HA2 (prolyl 4-hydroxylase subunit alpha 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Prolyl 4-hydroxylase subunit alpha-1
  • CELE_Y47D3B.10
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Properties