Protein Name forkhead box G1
Organism Homo sapiens
Gene ID 2290
Gene Symbol

FOXG1

UniProt P55316 (FOXG1_HUMAN)
Relationships Total Number of functionally related compound(s) : 435
Total Number of Articles : 293
Description

forkhead box G1

Gene Summary

This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020]

synonyms
  • forkhead box protein G1
  • brain factor 1
  • brain factor 2
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Properties