Protein Name | forkhead box G1 |
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Organism | Homo sapiens |
Gene ID | 2290 |
Gene Symbol | FOXG1 |
UniProt | P55316 (FOXG1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
435
Total Number of Articles : 293 |
Description |
forkhead box G1 |
Gene Summary |
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020] |
synonyms |
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Properties | |