| Protein Name | aminoadipate-semialdehyde synthase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10157 |
| Gene Symbol | AASS |
| UniProt | Q9UDR5 (AASS_HUMAN), A4D0W4 (A4D0W4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 9 |
Description |
aminoadipate-semialdehyde synthase |
| Gene Summary |
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008] |
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| Properties | |