Protein Name cytokine inducible SH2-containing protein
Organism Mus musculus
Gene ID 12700
Gene Symbol

Cish

UniProt Q62225 (CISH_MOUSE), Q8C3F4 (Q8C3F4_MOUSE)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 49
Description

cytokine inducible SH2-containing protein

Gene Summary

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within protein kinase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in liver; retina; and thymus primordium. Human ortholog(s) of this gene implicated in malaria and tuberculosis. Orthologous to human CISH (cytokine inducible SH2 containing protein). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytokine-inducible SH2-containing protein
  • cytokine-inducible SH2 protein
  • suppressor of cytokine signaling
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Properties