CPRiL

Protein Name	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Organism	Homo sapiens
Gene ID	1962
Gene Symbol	EHHADH
UniProt	Q08426 (ECHP_HUMAN)
Relationships	Total Number of functionally related compound(s) : 92 Total Number of Articles : 66
Description	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Gene Summary	The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
synonyms	peroxisomal bifunctional enzyme 3,2-trans-enoyl-CoA isomerase L-3-hydroxyacyl-CoA dehydrogenase L-bifunctional protein, peroxisomal PBE enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase multifunctional enzyme 1 peroxisomal enoyl-CoA hydratase ECHD FRTS3 L-PBE LBFP LBP MFE1 PBFE Click to show/hide the synonyms
Properties