Protein Name protein tyrosine phosphatase receptor type C
Organism Mus musculus
Gene ID 19264
Gene Symbol

Ptprc

UniProt P06800 (PTPRC_MOUSE), S4R1M0 (S4R1M0_MOUSE), Q8C6Q7 (Q8C6Q7_MOUSE)
Relationships Total Number of functionally related compound(s) : 248
Total Number of Articles : 278
Description

protein tyrosine phosphatase receptor type C

Gene Summary

Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • receptor-type tyrosine-protein phosphatase C
  • leukocyte common antigen
  • lymphocyte antigen 5
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Properties