| Protein Name | protein tyrosine phosphatase receptor type C |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19264 |
| Gene Symbol | Ptprc |
| UniProt | P06800 (PTPRC_MOUSE), S4R1M0 (S4R1M0_MOUSE), Q8C6Q7 (Q8C6Q7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
248
Total Number of Articles : 278 |
Description |
protein tyrosine phosphatase receptor type C |
| Gene Summary |
Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; regulation of cytokine production; and regulation of signal transduction. Acts upstream of or within several processes, including T cell activation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including alimentary system; cardiovascular system; hemolymphoid system; placenta; and skin. Used to study Alzheimer's disease and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency 105. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Jun 2025] |
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