Protein Name parathyroid hormone
Organism Mus musculus
Gene ID 19226
Gene Symbol

Pth

UniProt Q9Z0L6 (Q9Z0L6_MOUSE)
Relationships Total Number of functionally related compound(s) : 282
Total Number of Articles : 499
Description

parathyroid hormone

Gene Summary

Enables hormone activity. Involved in calcium ion homeostasis; magnesium ion homeostasis; and phosphate ion homeostasis. Acts upstream of or within several processes, including homeostasis of number of cells within a tissue; negative regulation of apoptotic process in bone marrow cell; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in 2nd branchial arch; 3rd branchial pouch; 3rd branchial pouch dorsal endoderm; foregut gland; and parathyroid gland. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Orthologous to human PTH (parathyroid hormone). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • parathyroid hormone
  • Pthp
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Properties