Protein Name parathyroid hormone
Organism Mus musculus
Gene ID 19226
Gene Symbol

Pth

UniProt Q9Z0L6 (Q9Z0L6_MOUSE)
Relationships Total Number of functionally related compound(s) : 282
Total Number of Articles : 499
Description

parathyroid hormone

Gene Summary

Enables hormone activity. Involved in calcium ion homeostasis; magnesium ion homeostasis; and phosphate ion homeostasis. Acts upstream of or within several processes, including negative regulation of apoptotic process in bone marrow cell; positive regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Is expressed in several structures, including branchial arch; foregut gland primordium; gut gland; and thymus. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Orthologous to human PTH (parathyroid hormone). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • parathyroid hormone
  • Pthp
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Properties