| Protein Name | ISG15 ubiquitin like modifier |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 9636 |
| Gene Symbol | ISG15 |
| UniProt | P05161 (ISG15_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
107
Total Number of Articles : 115 |
Description |
ISG15 ubiquitin like modifier |
| Gene Summary |
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012] |
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