Protein Name cystathionine gamma-lyase
Organism Homo sapiens
Gene ID 1491
Gene Symbol

CTH

UniProt P32929 (CGL_HUMAN)
Relationships Total Number of functionally related compound(s) : 195
Total Number of Articles : 442
Description

cystathionine gamma-lyase

Gene Summary

This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

synonyms
  • cystathionine gamma-lyase
  • cystathionase (cystathionine gamma-lyase)
  • cysteine desulfhydrase
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Properties