Protein Name serine (or cysteine) peptidase inhibitor, clade H, member 1
Organism Mus musculus
Gene ID 12406
Gene Symbol

Serpinh1

UniProt P19324 (SERPH_MOUSE)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 45
Description

serine (or cysteine) peptidase inhibitor, clade H, member 1

Gene Summary

Enables unfolded protein binding activity. Acts upstream of or within several processes, including chondrocyte development involved in endochondral bone morphogenesis; collagen biosynthetic process; and collagen fibril organization. Located in endoplasmic reticulum. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; metanephros; and skeleton. Used to study osteogenesis imperfecta type 10. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 10 and preterm premature rupture of the membranes. Orthologous to human SERPINH1 (serpin family H member 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • serpin H1
  • 47 kDa heat shock protein
  • beta enolase repressor factor 1
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Properties