Protein Name lymphotoxin beta receptor
Organism Homo sapiens
Gene ID 4055
Gene Symbol

LTBR

UniProt P36941 (TNR3_HUMAN)
Relationships Total Number of functionally related compound(s) : 73
Total Number of Articles : 62
Description

lymphotoxin beta receptor

Gene Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]

synonyms
  • tumor necrosis factor receptor superfamily member 3
  • lymphotoxin B receptor
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
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Properties