Protein Name thiopurine methyltransferase
Organism Mus musculus
Gene ID 22017
Gene Symbol


UniProt O55060 (TPMT_MOUSE), A0A0R4J018 (A0A0R4J018_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 15

thiopurine methyltransferase

Gene Summary

Enables thiopurine S-methyltransferase activity. Predicted to be involved in xenobiotic metabolic process. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm. Is expressed in metanephros. Used to study thiopurine S-methyltransferase deficiency. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

  • thiopurine S-methyltransferase
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