| Protein Name | thiopurine methyltransferase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22017 |
| Gene Symbol | Tpmt |
| UniProt | O55060 (TPMT_MOUSE), A0A0R4J018 (A0A0R4J018_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
16
Total Number of Articles : 15 |
Description |
thiopurine methyltransferase |
| Gene Summary |
Enables thiopurine S-methyltransferase activity. Predicted to be involved in xenobiotic metabolic process. Predicted to be located in cytoplasm. Is expressed in metanephros. Used to study poor metabolism of thiopurines. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and poor metabolism of thiopurines 1. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |