| Protein Name | MIB E3 ubiquitin protein ligase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 57534 |
| Gene Symbol | MIB1 |
| UniProt | Q86YT6 (MIB1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
220
Total Number of Articles : 296 |
Description |
MIB E3 ubiquitin protein ligase 1 |
| Gene Summary |
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013] |
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| Properties | |