Protein Name apolipoprotein B mRNA editing enzyme catalytic subunit 3G
Organism Homo sapiens
Gene ID 60489
Gene Symbol

APOBEC3G

UniProt Q9HC16 (ABC3G_HUMAN)
Relationships Total Number of functionally related compound(s) : 139
Total Number of Articles : 202
Description

apolipoprotein B mRNA editing enzyme catalytic subunit 3G

Gene Summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Mar 2017]

synonyms
  • DNA dC->dU-editing enzyme APOBEC-3G
  • APOBEC-related cytidine deaminase
  • APOBEC-related protein 9
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Properties