| Protein Name | immunoglobulin heavy constant mu |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16019 |
| Gene Symbol | Ighm |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
142
Total Number of Articles : 133 |
Description |
immunoglobulin heavy constant mu |
| Gene Summary |
Enables several functions, including antigen binding activity; identical protein binding activity; and immunoglobulin receptor binding activity. Involved in pre-B cell allelic exclusion. Acts upstream of or within several processes, including early endosome to late endosome transport; immunoglobulin mediated immune response; and positive regulation of B cell proliferation. Located in external side of plasma membrane; extracellular space; and perinuclear region of cytoplasm. Part of B cell receptor complex and immunoglobulin complex, circulating. Is active in cytoplasm. Is expressed in several structures, including brain; hemolymphoid system; intestine; liver; and testis. Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in agammaglobulinemia 1. Orthologous to human IGHM (immunoglobulin heavy constant mu). [provided by Alliance of Genome Resources, Jun 2025] |
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