Protein Name NPC intracellular cholesterol transporter 1 homolog 2
Organism Caenorhabditis elegans
Gene ID 176165
Gene Symbol

ncr-2

UniProt P34389 (NPC1B_CAEEL)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 1
Description

NPC intracellular cholesterol transporter 1 homolog 2

Gene Summary

Involved in cholesterol homeostasis; cholesterol transport; and nematode larval development. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in XXXL; XXXR; gonadal sheath cell; spermatheca; and ventral nerve cord. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C1. Orthologous to human NPC1 (NPC intracellular cholesterol transporter 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • NPC intracellular cholesterol transporter 1 homolog 2
  • CELE_F09G8.4
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Properties