Protein Name | neurofilament medium chain |
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Organism | Rattus norvegicus |
Gene ID | 24588 |
Gene Symbol | Nefm |
UniProt | P12839 (NFM_RAT) |
Relationships |
Total Number of functionally related compound(s) :
49
Total Number of Articles : 37 |
Description |
neurofilament medium chain |
Gene Summary |
Enables signaling receptor binding activity and toxic substance binding activity. Involved in several processes, including cellular response to estradiol stimulus; intermediate filament cytoskeleton organization; and nervous system development. Located in axon; neurofilament; and perikaryon. Used to study amyotrophic lateral sclerosis and congenital hypothyroidism. Biomarker of hypothyroidism; sciatic neuropathy; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Alzheimer's disease and human immunodeficiency virus infectious disease. Orthologous to human NEFM (neurofilament medium chain). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |