Protein Name | N-acetylneuraminate pyruvate lyase |
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Organism | Homo sapiens |
Gene ID | 80896 |
Gene Symbol | NPL |
UniProt | Q9BXD5 (NPL_HUMAN), A0A087WZ70 (A0A087WZ70_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
123
Total Number of Articles : 83 |
Description |
N-acetylneuraminate pyruvate lyase |
Gene Summary |
This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
synonyms |
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Properties | |