Protein Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Organism Mus musculus
Gene ID 18639
Gene Symbol

Pfkfb1

UniProt P70266 (F261_MOUSE), A2AFM9 (A2AFM9_MOUSE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Gene Summary

Enables fructose-2,6-bisphosphate 2-phosphatase activity. Involved in negative regulation of glycolytic process through fructose-6-phosphate. Predicted to be part of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex. Predicted to be active in cytosol. Orthologous to human PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
  • 6PF-2-K/Fru-2,6-P2ase liver isozyme
  • PFK-2/FBPase-2 gene A
Click to show/hide the synonyms
Properties