Protein Name ADAM metallopeptidase domain 19
Organism Mus musculus
Gene ID 11492
Gene Symbol

Adam19

UniProt O35674 (ADA19_MOUSE), Q3UHT3 (Q3UHT3_MOUSE), Q3UH67 (Q3UH67_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 4
Description

ADAM metallopeptidase domain 19

Gene Summary

This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]

synonyms
  • disintegrin and metalloproteinase domain-containing protein 19
  • MDC beta
  • Mel beta
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Properties