Protein Name reelin
Organism Mus musculus
Gene ID 19699
Gene Symbol

Reln

UniProt Q60841 (RELN_MOUSE)
Relationships Total Number of functionally related compound(s) : 82
Total Number of Articles : 114
Description

reelin

Gene Summary

Enables receptor ligand activity; serine-type peptidase activity; and very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including nervous system development; positive regulation of cell communication; and regulation of neurotransmitter receptor activity. Acts upstream of or within several processes, including nervous system development; peptidyl-tyrosine phosphorylation; and regulation of macromolecule metabolic process. Located in cytoplasm; dendrite; and extracellular matrix. Is active in extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; and familial temporal lobe epilepsy 7. Orthologous to human RELN (reelin). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • reelin
  • extracellular matrix serine protease
  • reeler
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Properties