| Protein Name | phospholamban |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18821 |
| Gene Symbol | Pln |
| UniProt | P61014 (PPLA_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
84
Total Number of Articles : 83 |
Description |
phospholamban |
| Gene Summary |
Enables ATPase inhibitor activity and protein homodimerization activity. Involved in several processes, including locomotor rhythm; negative regulation of calcium ion import into sarcoplasmic reticulum; and visual learning. Acts upstream of or within several processes, including muscle cell cellular homeostasis; regulation of calcium ion transport; and regulation of heart contraction. Located in sarcoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; ear; heart; nervous system; and skeleton. Used to study centronuclear myopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1P and hypertrophic cardiomyopathy 18. Orthologous to human PLN (phospholamban). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |