Protein Name C-X-C motif chemokine ligand 12
Organism Mus musculus
Gene ID 20315
Gene Symbol

Cxcl12

UniProt P40224 (SDF1_MOUSE), H7BX38 (H7BX38_MOUSE)
Relationships Total Number of functionally related compound(s) : 300
Total Number of Articles : 366
Description

C-X-C motif chemokine ligand 12

Gene Summary

This gene encodes a member of the alpha chemokine protein family. The encoded protein is secreted and functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4. The encoded protein plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

synonyms
  • stromal cell-derived factor 1
  • 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
  • chemokine (C-X-C motif) ligand 12
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Properties