Protein Name | Core-binding factor subunit beta homolog bro-1 |
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Organism | Caenorhabditis elegans |
Gene ID | 172158 |
Gene Symbol | bro-1 |
UniProt | Q95ZL9 (Q95ZL9_CAEEL) |
Relationships |
Total Number of functionally related compound(s) :
2
Total Number of Articles : 1 |
Description |
Core-binding factor subunit beta homolog bro-1 |
Gene Summary |
Enables transcription corepressor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of locomotion involved in locomotory behavior. Located in nucleus. Part of core-binding activity factor complex. Is expressed in several structures, including hypodermis; intestine; pharyngeal neurons; ray precursor cell; and uterine seam cell. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Orthologous to human CBFB (core-binding factor subunit beta). [provided by Alliance of Genome Resources, Jul 2025] |
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