Protein Name Core-binding factor subunit beta homolog bro-1
Organism Caenorhabditis elegans
Gene ID 172158
Gene Symbol

bro-1

UniProt Q95ZL9 (Q95ZL9_CAEEL)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 1
Description

Core-binding factor subunit beta homolog bro-1

Gene Summary

Enables transcription corepressor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of locomotion involved in locomotory behavior. Located in nucleus. Part of core-binding activity factor complex. Is expressed in several structures, including hypodermis; intestine; pharyngeal neurons; ray precursor cell; and uterine seam cell. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Orthologous to human CBFB (core-binding factor subunit beta). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Core-binding factor subunit beta homolog bro-1
  • CELE_F56A3.5
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Properties