| Protein Name | malate dehydrogenase 2, NAD (mitochondrial) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17448 |
| Gene Symbol | Mdh2 |
| UniProt | P08249 (MDHM_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
74
Total Number of Articles : 60 |
Description |
malate dehydrogenase 2, NAD (mitochondrial) |
| Gene Summary |
Enables L-malate dehydrogenase (NAD+) activity. Involved in gluconeogenesis; malate-aspartate shuttle; and tricarboxylic acid cycle. Located in membrane. Is active in mitochondrial matrix. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 51. Orthologous to human MDH2 (malate dehydrogenase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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