Protein Name gastrin releasing peptide
Organism Homo sapiens
Gene ID 2922
Gene Symbol


UniProt P07492 (GRP_HUMAN), A0A140VJM7 (A0A140VJM7_HUMAN)
Relationships Total Number of functionally related compound(s) : 809
Total Number of Articles : 802

gastrin releasing peptide

Gene Summary

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

  • gastrin-releasing peptide
  • bombesin
  • neuromedin C
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