Protein Name Cbl proto-oncogene C
Organism Homo sapiens
Gene ID 23624
Gene Symbol

CBLC

UniProt Q9ULV8 (CBLC_HUMAN)
Relationships Total Number of functionally related compound(s) : 76
Total Number of Articles : 109
Description

Cbl proto-oncogene C

Gene Summary

This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • E3 ubiquitin-protein ligase CBL-C
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence c
  • Cas-Br-M (murine) ectropic retroviral transforming sequence c
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Properties